That is very important, due to the fact that the way a protein in the body folds figures out if a pharmaceutical will be able to bind to that protein and be reliable. To put it simply, we have to understand how these proteins fold if we want a drug to work. Historically, this has been an experimental procedure (self-driving cars). Today, Alpha, Fold can anticipate protein folding with 92. 4% precision. That's going to make it a lot easier to produce drugs that do what they're designed to do. This was a development nearly no one noticed. However it's going to have extensive implications for curing illness. I forecast that Alpha, Fold will be 98% precise by the end of 2021.
And, naturally, there will be a lot of investment chances in this space, too. Shifting subjects It's going to be a great year for bitcoin. I'm bullish on it in 2021 (toxic tech 5 tech darlings). That said, I still think bitcoin will continue to be unpredictable. We're close to all-time highs. I would not be amazed if it pulled back maybe considerably before going greater - biotech stock. I've been covering bitcoin for a long time now. One of the very first research reports I ever published was on bitcoin. That was in June 2015. At the time, bitcoin was trading for about $240. Bitcoin trades for over $34,000 today.
However at the time of that preliminary recommendation, I titled my report "What's the Big Deal With Bitcoin?" That reveals you where the conversation was at the time. We were mostly educating readers. But that's not the big concern any longer. Now we're seeing institutional money lastly take an interest in bitcoin. Massachusetts Mutual Life Insurance took a $100 million stake in bitcoin in December. This is not some little, specific niche business. Mass, Mutual is a relied on 170-year-old institution. So consider that. In 5 years, we went from informing readers on what bitcoin is to a business like Mass, Mutual taking a $100 million stake.
And that's a huge reason I'm bullish on it this year. democratic republic. Regards, Jeff Brown, Editor, The Bleeding Edge I have a bonus offer prediction 2020 was a record year for IPOs. 552 U.S. business went public the most in more than twenty years. These companies raised an overall of $172 billion. That's an all-time high beating the previous annual record by 43%. I anticipate 2021 will be another record year in IPOs. There are numerous great private business on the edge of hitting the public markets And I have actually been working on a brand-new method for you to invest even before these companies go public.
This opportunity has been developing over the last couple of years. I can't wait to tell you everything about it. Join me tomorrow at 8 p. m. ET for my Pre-IPO Code Event to find out all the information. Go right here to schedule your area free of charge.
Emma Walsh here, handling editor of the Journal. Regular Diary readers understand that tech isn't our usual beat (the legacy report prediction). And when it concerns tech investing, we leave it to the experts. Thankfully, we have several such experts in our Rolodex. Our coworker Jeff Brown will recognize to our longtime readers. He is one of the most accomplished tech investing experts we understand (toxic tech 5 tech darlings). In fact, he had a number of triple-digit returns in his Brownstone Research portfolios in 2015. Here's what Jeff believes the tech sector will bring us in 2021 Each year, I like to take an appearance at the big photo and predict what's just around the corner.
That consists of things like 5G networks, biotech, artificial intelligence, and far more. These trends are experiencing exponential development and producing amazing opportunities for financiers. I wish to make certain all our readers are prepared for what's next. And with that in mind, let me draw the picture of what I see can be found in the next 12 months Our new 5G (fifth-generation) cordless networks are a topic I have actually been covering for years now. democratic republic. But in spite of what numerous readers may believe, this is a pattern that's simply starting. Even though the COVID-19 pandemic interfered with supply chains last year, an excellent 250 million 5G-enabled devices were still offered.
And all of this ultimately resulted in Apple postponing the release of the 5G-enabled i, Phone 12 by two months (biotech stocks). Losing two months of production and sales actually impacts the number of 5G gadgets are sold in the fiscal year. When you consider all of that, selling 250 million systems is exceptional. More notably, the hold-ups brought on by the pandemic created a lots of bottled-up need. And that demand is now going to be pressed into 2021. In fact, I forecast that more than 500 million 5G devices will be delivered in 2021 - jeff brown top stock pick 2021. Which's not my only 5G forecast When I've talked about 5G in the past, I've described its 3 different stages.
In Phase 2, 5G devices go on sale. 5G phones and other products start to reach customers. And in Stage Three, 5G services start to be provided (second wave). That's when we start to see applications working on 5G networks. Think about things like massive multiplayer video games over a mobile phone. That's not possible with 4G. It will be with 5G. And my 2nd 5G prediction for 2021 is that we will begin Stage 3 by this summertime. This begins something of a virtuous cycle: Many people don't really care about the innovation. But they will care if there are interesting applications that can only be accessed with a 5G phone.
That results in more 5G apps being developed. In truth, 5G is going to open up a suite of extraordinary applications: self-driving vehicles, the Internet of Things, robotic surgical treatment, and more. All of these technologies need 5G. The investment opportunities going forward will be enormous. Stepping far from 5G, the next crucial innovation I anticipate in 2021 is CRISPR genetic modifying. CRISPR represents "clustered regularly interspaced brief palindromic repeat." It's a mouthful. However it's one of the most amazing developments in biotechnology. At a high level, CRISPR is a technology that can edit our hereditary makeup as if it were software application.
The program can crash or not work properly. CRISPR utilizes a comparable idea but with our hereditary code. "Typos" in our genome can result in disease. CRISPR can correct these "typos." For several years, CRISPR was mainly a niche innovation that wasn't well comprehended. And during that time, there were actually just 3 companies operating in this area. But things are altering. CRISPR is no longer simply theoretical. We're seeing real results. We're dealing with illness and seeing that this innovation simply works. And as an outcome, a "second crop" of early-stage CRISPR companies is going public and delivering amazing returns. This whole industry is effectively a greenfield chance.
There's space for lots of companies to exist in this area. tech predictions. And there will be more. That's my prediction for CRISPR in 2021. I forecast that 2 or three more hereditary modifying business will hold their IPOs. Sticking with biotechnology, we are seeing incredible things taking place at the convergence of biotech and synthetic intelligence (AI). Google's AI subsidiary, Deep, Mind, simply revealed at the end of 2020 that its newest Alpha, Fold software can precisely anticipate the folding of a protein based solely on its amino acid sequence with 92. 4% precision. That is essential due to the fact that the way a protein in the body folds determines if a pharmaceutical will be able to bind to that protein and be reliable.
Historically, this has been an experimental process. Now, Alpha, Fold can forecast protein folding with 92. 4% precision. That's going to make it much simpler to develop drugs that do what they're created to do. And here's my next forecast. I forecast that Alpha, Fold will be 98% precise by the end of 2021. And we will see not simply one however numerous drug therapies produced using this technology. This was among those developments that practically no one noticed. But it's going to have profound implications for treating illness. And, obviously, there will be lots of investment chances in this space, too.
It's going to be a great year for bitcoin. I'm bullish on it in 2021. That said, I still think bitcoin will continue to be unpredictable. We're close to all-time highs. I wouldn't be surprised if it pulled back possibly significantly before going greater. I have actually been covering bitcoin for a long period of time now. One of the first research study reports I ever released was on bitcoin - legacy report prediction. That remained in June 2015. At the time, bitcoin was trading for about $240. Bitcoin trades for over $40,000 today. So that's a 16,500%+ return on financial investment for anyone who followed my recommendation. But at the time of that initial recommendation, I entitled my report, "What's the Big Deal With Bitcoin?" That reveals you where the conversation was at the time.
But no one is asking that concern anymore. Now, we're seeing institutional cash lastly taking an interest in bitcoin. The big news was that Massachusetts Mutual Life Insurance coverage took a $100 million stake in bitcoin in December. This is not some small, niche business. white house. Mass, Mutual is a 150-year-old organization. So believe about that. In 5 years, we went from informing readers on what bitcoin is to a company like Mass, Mutual taking a $100 million stake. The institutional adoption of bitcoin will continue. Which's a big reason why I'm bullish on it this year. Regards, Jeff Brown, Editor, The Bleeding Edge I have another bonus forecast In 2021, we're going to have another record year in IPOs. One site reports that Jeff Brown is worth about $27. 5 million and claims the details is up to date as of February 2021, however we could not separately verify this claim. Provided Jeff Brown's past, he likely has a substantial net worth, however we can't hammer down a precise figure at this minute. Brown is best known for his sage-like capability to choose winning innovation stocks. He invested more than 25 years looking into innovation companies like Qualcomm, NXP semiconductors, and Juniper Networks. Brown's substantial experience offers him an exceptional perspective on the market. He's constantly on the hunt for new opportunities, and he shares much of his finest picks in the Near Future Report.
That's full marks, but it's not absurdly reasoned. Brown has an exceptional track record as a stock-picker, and he effectively anticipated a few of the greatest financial events of the previous 20 years. Although he does not appear to release his choices to the general public, the service's success is a direct indication of Brown's stock-picking expertise. Nobody on Wall Street gets it right each time, however Jeff Brown's precise predictions have earned him legions of dedicated followers. That says a lot about his capability. The Future Report is released by Brownstone Research study, a popular monetary research publisher. Brownstone Research study offers numerous research study services with a wide variety of expertises - jeff brown tech stock 2021.
The company is also associated with Bonner & Partners, another well-respected research study publisher - jeff bezos. On its website, Brownstone states its mission is to supply retail investors with professional-grade research: "For too long, the very best investment research study has actually not been offered to specific financiers. It has been usually scheduled for financial investment banks, hedge funds, private equity, and high-net-worth clients. melania trump. The objective of Brownstone Research is to make that type of proprietary research readily available to any investors looking to acquire an edge in the marketplaces. The objective is easy to deliver special and profitable investment research discovered no place else." -Brownstone Research study website excerpt from the Jeff Brown is the creator of Brownstone Research, and he likewise functions as the company's Chief Investment Analyst.
With Brown directing the ship, Brownstone Research study is a powerhouse publisher with lots to offer its customers. After years of constant success at the helm of top-tier companies like Tesla and Space, X, Elon Musk is a household name throughout most of America. If you know even a bit about the marketplace, you understand that he has a credibility as a King Midas of sorts. last year. Whatever he touches relies on gold! Jeff is aware of Elon Musk's executive prowess, so he always has an eye out for the Silicon Valley rock star's next relocation. This time, Jeff has an early lead on Elon's next huge job.
In fact, Brown thinks S.A.V. jeff brown predictions 2021. could be "the biggest trend of the 2020s, and he's not alone. Take a look at these quotes from other popular S.A.V. bulls: Elon's next big act will be weding two innovative innovations: artificial intelligence and electric vehicles. Musk hopes the combination will assist him develop the first fully-autonomous, self-driving vehicles ever. It's absolutely nothing except the automotive industry's Holy Grail. As you know, electric vehicles and self-driving car stocks have been big this year, however the Wall Street device has actually been big on buzz without much tangible outcome. Regardless of a drastic boost in competition over the past couple of years, Brown still believes Musk has the finest possibility of putting it all together.
tech could be the magic string that connects everything together. S.A.V. represents Shared Autonomous Lorry, and it could be the future of transportation. Generally, this innovation would enable you to rent out your cars and truck as a self-governing, self-driving taxi when you're not utilizing it. You merely get out of the car and press a button on an app that informs the car to "sign up with the fleet." Next thing you know, you're unwinding on your sofa while your cars and truck shuttles ride-sharers around town. Best of all, you get to keep a significant chunk of the profits. It sounds outrageous, but it could be closed than you think.